The Science

Built on Clinical Research and Disclosed Doses.

Every ingredient in FLOTE RADIANCE was selected on published and supplier clinical evidence, not marketing trends — and every amount is disclosed. Here's the science.

A clinically studied system the 13-ingredient Inner Crown™ oral formula and the nine-active Liquid Halo™ precision serum, every dose disclosed. Zero proprietary blends.

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Clinical Evidence

The Evidence Table

Every clinically studied active in the system, its disclosed dose, and exactly what kind of evidence stands behind it — 5 peer-reviewed, journal-published studies and 5 supplier-generated clinical or in vitro dossiers. We label each one honestly rather than blur the difference.

ActiveFormula & DoseEvidence TypeKey Study
Serevelle™ Saw Palmetto295 mg oral + 1.0% topicalPeer-reviewed studyAblon G. "The Safety and Efficacy of a Novel Saw Palmetto (Serenoa repens) Extract for Promoting Hair Growth in Adults With Self-Perceived Thinning Hair: 180-Day Results." J Cosmet Dermatol. 2026;25(2):e70717. PMID: 41652806.
KSM-66® Ashwagandha250 mg oral (5% withanolides)Peer-reviewed studyChandrasekhar K, Kapoor J, Anishetty S. "A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults." Indian J Psychol Med. 2012;34(3):255–262. PMID: 23439798.
AnaGain™ Nu100 mg oral + 1.5% topicalPeer-reviewed studyGrothe T, Wandrey F, Schuerch C. "Short communication: Clinical evaluation of pea sprout extract in the treatment of hair loss." Phytother Res. 2020;34(2):428–431.
Ferrochel® Iron25 mg oral (139% DV)Peer-reviewed studyMilman N, Jønsson L, Dyre P, Pedersen PL, Larsen LG. "Ferrous bisglycinate 25 mg iron is as effective as ferrous sulfate 50 mg iron in the prophylaxis of iron deficiency and anemia during pregnancy in a randomized trial." J Perinat Med. 2014;42(2):197–206. PMID: 24152889.
Redensyl™3.0% topicalSupplier clinical dataChajra H, Lefevre F, Auriol D. "Native Polyphenols to Kick-start Hair Regrowth." Cosmetics & Toiletries. 2017;132(6):24–35.
ETERWELL™ HAIR0.5% topicalSupplier clinical dataDSM-Firmenich in-house technical data — ETERWELL™ HAIR product dossier and SEPAWA Congress 2025 presentation.
BeauPlex® VH0.5% topicalSupplier clinical dataDSM-Firmenich in-house clinical dossier — randomized, double-blind, placebo-controlled in vivo study, 60 volunteers, 5-month daily use (unpublished).
COLHIBIN™ CB0.5% topicalSupplier clinical dataDSM-Firmenich Colhibin CB technical dossier — in vitro MMP-1 (collagenase) inhibition data (unpublished).
BOND AID™ + OXY-229™ CB1.0% topicalSupplier clinical dataDSM-Firmenich, "dsm-firmenich Unveils Bond Aid with OXY 229 CB" (2025) — in-house technical and press dossier.
GHK-Cu Copper Tripeptide0.5% topicalPeer-reviewed studyUno H, Kurata S. "Chemical agents and peptides affect hair growth." J Invest Dermatol. 1993;101(1 Suppl):143S–147S. PMID: 8326148.

GHK-Cu copper tripeptide is patented rather than trademarked and is held to the same disclosure standard as every other active in the Liquid Halo™ serum. Some studies above test a different dose than the amount disclosed in our formula; the amounts in the "Formula & Dose" column are FLOTE RADIANCE's own disclosed doses, not necessarily the exact dose used in the cited research. Individual results vary. This information is for educational purposes and is not intended to diagnose, treat, cure, or prevent any disease.

Serevelle™ is a trademark of Valensa International. KSM-66® is a registered trademark of Ixoreal Biomed. AnaGain™ Nu is a trademark of Mibelle Biochemistry. Ferrochel® is a registered trademark of Balchem. Redensyl™ is a trademark of Givaudan (Active Beauty). ETERWELL™ HAIR, BeauPlex® VH, COLHIBIN™, BOND AID™, and OXY-229™ are trademarks of DSM-Firmenich.

Multi-Pathway Approach

Hair Thins for Six Reasons. We Addressed All Six.

Thinning hair is the result of multiple converging root causes. FLOTE RADIANCE addresses all six biological pathways at once, with named ingredients at disclosed amounts.

Primary Driver

DHT Defense

Serevelle™ (295 mg) and Zinc Picolinate (20 mg) work synergistically to inhibit 5-alpha-reductase, the enzyme that converts testosterone into DHT — the primary hormone responsible for follicle miniaturization.

Serevelle™ 295 mg · Zinc Picolinate 20 mg

Hormonal Balance

Stress & Hormonal Balance

KSM-66® Ashwagandha has been studied for its effect on cortisol, the hormone associated with stress-induced shedding. Mucuna Pruriens supports dopamine pathways and hormonal equilibrium.

KSM-66® 250 mg · Mucuna Pruriens 187 mg

Blood Flow

Scalp Circulation & Nutrient Delivery

Ginkgo biloba GB761, standardised to 24% flavone glycosides, and niacinamide are studied for their effect on nitric oxide and scalp microcirculation — the delivery route that carries the rest of the formula to the dermal papilla.

Ginkgo Biloba 157 mg · Gotu Kola 220 mg · Niacin (as Niacinamide) 16 mg NE

Growth Reactivation

Follicle Activation

AnaGain™ Nu, a germinated pea seed extract from Mibelle Biochemistry, has been studied for its signalling effect at the dermal papilla. In Mibelle's clinical dossier the extract showed a significant reduction in shedding at 28 days (p<0.002).

AnaGain™ Nu 100 mg · Mibelle Biochemistry clinical dossier, 2022

Nutrition

Structural Nutrition

Moringa, Ferrochel® Iron and Biotin supply the building blocks of the hair shaft. Ferrochel® is Balchem's TRAACS® amino acid chelate, delivering 139% DV of iron and studied at up to 5× the absorption of standard iron forms (Balchem absorption study set, 2023).

Moringa 150 mg · Ferrochel® Iron 25 mg · Biotin 5000 mcg

Longevity

Antioxidant Protection

Triphala, Selenium, and Gotu Kola form a comprehensive antioxidant matrix that protects dividing follicle cells from oxidative senescence and scalp inflammation.

Triphala 150 mg · Selenium 100 mcg · Gotu Kola 220 mg

Ingredient Science

85%
Free fatty acids in Serevelle™ CO2 extract — vs. 20–25% in standard saw palmetto extracts

Valensa International supplier technical data. Ingredient-level finding; individual results vary.

The FLOTE Difference

The Category Sells Fog. We Sell Receipts.

See how FLOTE RADIANCE stacks up against the leading competitor.

Feature
FLOTE RADIANCE
Leading Competitor
DHT-Defense Ingredient
Serevelle™ CO2 extract — standardized to 85% free fatty acids vs. 20–25% in standard extracts
Standard saw palmetto extract — 20–25% free fatty acids
Named Ingredients
13 of 13 disclosed
Proprietary blend
Clinically Studied Actives
13-ingredient oral formula + 9-active precision serum
1 proprietary complex
Formula Transparency
Full dosage disclosure
Proprietary blend (hidden)
Unisex Formula
Yes — one formula for all
No — separate SKUs
Access Model
Free 90-day program for qualifying members — no subscription required
Monthly subscription
Topical Serum System
9 actives from 5 named suppliers
Not included
Daily Capsule Burden
3 capsules
4 capsules
Program Support
Weekly check-ins & guidance
None
Satisfaction Guarantee
30-day satisfaction guarantee
Unknown

Clinical figures describe the named ingredients, not the finished product. The 85% free-fatty-acid standardization of Serevelle™ supercritical CO2 saw palmetto extract, vs. 20–25% in standard saw palmetto extracts, is per Valensa International's supplier technical data. Individual results vary.

Questions

Evidence, explained

What does “clinically studied active” mean?

A clinically studied active is a named ingredient from a specific manufacturer with its own research record — like Serevelle™ or Redensyl™ — rather than an unnamed material folded into a proprietary blend. The two-step FLOTE RADIANCE system pairs the 13-ingredient Inner Crown™ oral formula with the nine-active Liquid Halo™ precision serum — including patented GHK-Cu copper tripeptide — each active disclosed at its exact dose.

Is there published research behind these ingredients?

5 of the 10 actives in the evidence table below — Serevelle™, KSM-66®, AnaGain™ Nu, Ferrochel®, and GHK-Cu — have been studied in peer-reviewed, journal-published research. The remaining 5 — Redensyl™, ETERWELL™ HAIR, BeauPlex® VH, COLHIBIN™ CB, and BOND AID™ + OXY-229™ CB — are supported by supplier-generated clinical or in vitro data that hasn't been published in an independent, peer-reviewed journal. We label each row by its actual evidence type rather than implying every active carries the same level of substantiation.

Does a published study mean FLOTE RADIANCE itself was tested?

No. Every citation below tests the named ingredient — often at a specific dose, from a specific supplier — not the finished FLOTE RADIANCE formula, and some published doses differ from the amount disclosed in our formula. Where that's the case, we still cite the ingredient-level research because it's the best available evidence for that active, but we're not claiming our finished product was the subject of the clinical trial.

What is “supplier clinical data,” and why do you use it?

Some of our ingredients are new enough, or specialized enough, that no independent peer-reviewed study exists yet — in those cases the only testing available is the manufacturer's own in vitro or in vivo data. We disclose this openly and label it “Supplier clinical data” rather than presenting it as independent science, because we'd rather tell you exactly what evidence exists than imply more than we can prove.

Sources

References

  1. 1.Peer-reviewed studyAblon G. "The Safety and Efficacy of a Novel Saw Palmetto (Serenoa repens) Extract for Promoting Hair Growth in Adults With Self-Perceived Thinning Hair: 180-Day Results." J Cosmet Dermatol. 2026;25(2):e70717. PMID: 41652806.
  2. 2.Peer-reviewed studyChandrasekhar K, Kapoor J, Anishetty S. "A Prospective, Randomized Double-Blind, Placebo-Controlled Study of Safety and Efficacy of a High-Concentration Full-Spectrum Extract of Ashwagandha Root in Reducing Stress and Anxiety in Adults." Indian J Psychol Med. 2012;34(3):255–262. PMID: 23439798.
  3. 3.Peer-reviewed studyGrothe T, Wandrey F, Schuerch C. "Short communication: Clinical evaluation of pea sprout extract in the treatment of hair loss." Phytother Res. 2020;34(2):428–431.
  4. 4.Peer-reviewed studyMilman N, Jønsson L, Dyre P, Pedersen PL, Larsen LG. "Ferrous bisglycinate 25 mg iron is as effective as ferrous sulfate 50 mg iron in the prophylaxis of iron deficiency and anemia during pregnancy in a randomized trial." J Perinat Med. 2014;42(2):197–206. PMID: 24152889.
  5. 5.Supplier clinical dataChajra H, Lefevre F, Auriol D. "Native Polyphenols to Kick-start Hair Regrowth." Cosmetics & Toiletries. 2017;132(6):24–35.
  6. 6.Supplier clinical dataDSM-Firmenich in-house technical data — ETERWELL™ HAIR product dossier and SEPAWA Congress 2025 presentation.
  7. 7.Supplier clinical dataDSM-Firmenich in-house clinical dossier — randomized, double-blind, placebo-controlled in vivo study, 60 volunteers, 5-month daily use (unpublished).
  8. 8.Supplier clinical dataDSM-Firmenich Colhibin CB technical dossier — in vitro MMP-1 (collagenase) inhibition data (unpublished).
  9. 9.Supplier clinical dataDSM-Firmenich, "dsm-firmenich Unveils Bond Aid with OXY 229 CB" (2025) — in-house technical and press dossier.
  10. 10.Peer-reviewed studyUno H, Kurata S. "Chemical agents and peptides affect hair growth." J Invest Dermatol. 1993;101(1 Suppl):143S–147S. PMID: 8326148.

FLOTE RADIANCE is a cosmetic and nutritional supplement system, not a drug, and is not intended to diagnose, treat, cure, or prevent any disease. Individual results vary.

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